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From Genetics to Radiology: The Journey of Ashley Lynn Severance-Masello

Post Date: May 26, 2026
From Genetics to Radiology: The Journey of Ashley Lynn Severance-Masello

Ashley Lynn Severance-Masello, who serves as a project manager for Radiology Operations at Cincinnati Children’s, plays a key part in ensuring that major projects move forward effectively and efficiently. Her responsibilities include tracking and monitoring progress across a range of initiatives. While some projects require oversight and coordination, others call for a more hands-on approach where Ashley actively helps drive momentum and guide teams toward success. 

Her diverse background in genetics, research, and problem-solving uniquely positions her to navigate complex challenges and deliver results that support both clinical teams and patient care. 

Ashley was born in Jackson, Michigan, where she grew up alongside her younger brother, John. Her early years were filled with the energy of youth sports, particularly softball. While she spent many seasons on the field, she fondly recalls that batting was always her favorite part of the game—a small but telling sign of her drive to focus on the moments that mattered most. 

Before embarking on her academic and professional journey, Ashley spent over five years working at Sears, where she sold televisions. This experience helped shape her strong communication skills and work ethic. These tools would later serve her well in both science and leadership roles. 

Ashley attended Albion College, a small liberal arts school in lower Michigan. It was there that her passion for learning deepened and where she met her future husband, Paulo Masello. This chapter of her life combined intellectual growth with personal milestones, setting the foundation for everything that followed. 

Driven by her interest in science, Ashley pursued a PhD in genetics, completing the program in 2018. Her studies were rigorous and demanding, but they also opened doors to new opportunities and discoveries. 

After earning her PhD, Ashley and her spouse relocated to Cincinnati, where she began a postdoctoral position focused on maternal fetal tolerance during pregnancy. This work placed her at the intersection of cutting-edge research and real-world impact, contributing to a deeper understanding of how the body supports and protects developing life. 

Cincinnati also became home in another, even more meaningful way. In 2019, Ashley welcomed her child, Samantha (Sami) Lynn Masello. Parenthood added a joyful new dimension to her life—one that now shapes much of her time outside of work. 

Ashley’s favorite activities revolve around spending time with Sami. Their days are often filled with imaginative play and simple joys: dolls (especially Monster High), pretend pet hospitals, camping adventures, trips to the park, and visits to the library. They also enjoy crafting together and attending playdates, birthday parties, and swimming outings. These moments reflect Ashley’s belief that the most meaningful investments are made in time spent together. 

When she does find time to unwind, Ashley enjoys family-friendly entertainment. The last movie she watched was Disney’s Wish, and her most recent read was Little People, Big Dreams: Martin Luther King Jr.—a book that reflects both her intellectual curiosity and her desire to share meaningful stories with her child. 

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About the author: Glenn Miñano

Glenn Miñano is a media specialist in the Department of Radiology, providing graphic design, photography, printing, video services, and administration of the department’s online properties. His works have been published in several medical articles, such as the American Journal of Radiology and the American Institute of Ultrasound. He has been providing these services to the Radiology Department since 1996.

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About the editor: Meredith Towbin

Editor: Meredith Towbin

About The Department

The Radiology Department at Cincinnati Children's is a leader in pediatric diagnostic imaging, radiology research, and radiation dose reduction.

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